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OneTouchInvest Reports Eli Lilly’s (LLY) Approval of Zepbound, an Obesity Drug

Eli Lilly’s Zepbound approval signals a significant entry into the obesity drug market, balancing financial strength and CEO confidence amidst safety considerations.

Genève, Switzerland, November 15, 2023 – Eli Lilly and Company (LLY) has recently secured a significant milestone with the FDA’s approval of tirzepatide, a drug already recognized for treating Type 2 diabetes under the name Mounjaro. This breakthrough, allowing the drug to be marketed as Zepbound for chronic weight management, positions Eli Lilly as a key player in the expanding obesity drug market. With an estimated 650 million adults globally affected by obesity and about 40% of the U.S. adult population grappling with this health concern, the approval addresses a critical medical need. In the following sections of this article, an expert from OneTouchInvest has unveiled the details of this development.

Zepbound’s Approval and Market Dynamics

The FDA’s recent approval of Zepbound solidifies Eli Lilly’s standing in the obesity drug market, positioning the company as a formidable competitor. The approval not only allows for the expanded use of tirzepatide, Eli Lilly’s blockbuster drug previously known as Mounjaro, for Type 2 diabetes treatment, but it also opens doors for chronic weight management. This regulatory milestone places Eli Lilly in a prime position to tap into the burgeoning obesity drug market, which market analysts predict could reach a staggering $100 billion industry by 2030. With Zepbound expected to hit the U.S. market by the end of the year, Eli Lilly is poised to address the escalating demand for effective weight management solutions.

Mechanism of Action and Clinical Trials

Zepbound’s mechanism of action is intricately tied to its unique combination of two naturally produced hormones, GLP-1 and GIP. By activating these hormones, the drug slows stomach emptying, prolonging the feeling of fullness and suppressing hunger signals in the brain. The FDA’s approval was based on rigorous late-stage trials, with results showcasing the drug’s efficacy in promoting weight loss. In a study involving over 2,500 adults with obesity but without diabetes, participants experienced an average weight loss of 16% after 72 weeks of Zepbound usage. Higher doses demonstrated even more substantial weight loss, further establishing the drug as a promising solution for individuals struggling with obesity.

Market Competition and Pricing Strategy

Entering a competitive landscape alongside weight loss drugs like Ozempic, Zepbound, and Wegovy faces the challenge of supply constraints due to heightened demand. Despite these challenges, Eli Lilly strategically priced Zepbound at approximately $1,060 for a month’s supply, positioning it as a slightly more affordable option compared to Wegovy. Recognising the importance of accessibility, the company is launching a commercial savings card program. This initiative aims to make Zepbound more affordable for patients with insurance coverage, potentially reducing the out-of-pocket expenses to as low as $25 for a one-month or three-month prescription.

Financial Performance and Earnings Report

Evaluating Eli Lilly’s financial performance provides a broader context for understanding the company’s current standing. Over the past five days, the stock has experienced a positive change of +4.16%, reflecting investor confidence. The one-month change stands at +2.10%, while the more impressive six-month and one-year changes are +35.68% and +60.41%, respectively. The latest earnings report, released on November 2, 2023, reveals an EPS of 0.1, surpassing the forecast of -0.2. Additionally, the revenue of 9.5B exceeded the forecast of 8.97B, suggesting a robust financial outlook for Eli Lilly.

Challenges in Access and Insurance Coverage

Despite the potential benefits Zepbound offers, challenges persist in ensuring broader access to the drug. Many insurance companies are dropping weight loss drugs from their plans, citing the high costs associated with covering these medications. Eli Lilly acknowledges this hurdle and is committed to collaborating with healthcare, government, and industry partners to facilitate broader access. The company’s proactive stance reflects an understanding of the evolving dynamics of insurance coverage for weight loss drugs and a commitment to overcoming these challenges.

Safety Concerns and Regulatory Warnings

While Zepbound presents a promising solution to obesity, it is essential to acknowledge the safety concerns outlined by the FDA. The medicine has been linked to adverse effects such as diarrhoea, nausea, and, notably, thyroid C-cell tumours in rats. The impact of this effect on humans remains unclear. The FDA recommends against using Zepbound in individuals who have previous cases of medullary thyroid cancer or Multi Endocrine Neoplasia type 2. Additionally, caution is warranted when considering coadministration with other GLP-1 targeting drugs, as safety and effectiveness in combination have not been established.

Future Outlook and CEO’s Assurance

Looking ahead, Eli Lilly’s CEO, David Ricks, expresses confidence in the company’s ability to meet the increasing demand for Zepbound. Despite potential concerns about supply, Ricks reassures stakeholders that the company is fully prepared for a robust Zepbound launch by the end of the year. Moreover, efforts are underway to enhance production capacity for tirzepatide, signalling Eli Lilly’s commitment to addressing potential supply challenges. The CEO’s proactive communication provides investors with assurance regarding the company’s readiness to navigate the dynamic landscape of the obesity drug market.



In conclusion, Eli Lilly’s approval of Zepbound marks a significant stride in addressing the global challenge of obesity and overweight conditions. As the company navigates the intricacies of market competition, insurance coverage, and safety considerations, its financial outlook remains positive. Investors, buoyed by recent favourable changes and the commitment to expanding access, are likely to keep a keen eye on Eli Lilly’s stock performance as the company continues to pioneer innovative solutions for weight management.

Important Notice: This article is purely informational and doesn’t offer trading or financial advice. Its content is not intended to be investment advice. We do not guarantee the validity of the information, especially when it pertains to third-party references or hyperlinks.


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Company: OneTouchInvest

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Location:Genève, Switzerland